(C) Challenging cells with 2 µM Tg (D) or irradiating cells with 5 Gy x rays elicits progressive decrease in Mag-Fluo-4 fluorescence in ER with concomitant increase in cytosol. (B) In untreated control cells, the Mag-Fluo-4 fluorescence in the ER remains constant. (A) Fluorescent images of representative Jurkat cells loaded with Mag-Fluo-4 (green, first column) and stained with ER tracker red (magenta, second column) exhibit colocalization of both fluorescent signals in merged image (third column). Cascadea collects no data, outside of opt-in anonymous crash reports provided by Apple.Fluorescent sensor Mag-Fluo-4 reports depletion of ER Ca 2+ in Jurkat cells as a response to irradiation. Support for the Touch Bar on MacBook Pro.Native support for Macs with Apple silicon (such as Apple's M1).Exclude specific sites from a style to prevent conflicts or override a global style.
Cascadea armament update#
Have Cascadea automatically update your imported styles on launch.See which styles are active on a page right from Cascadea's toolbar icon in Safari, and double-click to open a style right in the Style Editor.Easily import and export your entire style database from Preferences.
Cascadea armament install#
Cascadea armament code#
Or, if you prefer your own code editor, you can easily import a CSS file into and out of Cascadea. Open multiple styles in tabs, configure rules for precisely which sites to apply a style, and watch Safari update to reflect your changes each time you save your CSS. Cascadea has a fully-featured Style Editor for writing CSS as well as the Stylus and Less preprocessor languages, including autocompletion, syntax highlighting, automatic indentation, code folding, beautification, multi-cursor support, multiple color themes and font options, and more. Once installed, Cascadea's fast native UI lets you quickly and easily configure settings for each style, change the order in which they apply, keep them up to date, and more.Ĭascadea is also a super-powerful tool for CSS developers, both for writing new custom styles or even as part of a web development workflow. Cascadea supports popular custom style websites, styles written in the UserCSS format, or even plain CSS files. It's super easy to install styles - just go to a compatible style in Safari, and you'll see an option to install it in Cascadea. Cascadea gives you the freedom to paint the web in your own colors. Give that super-bright website a darker theme that's easier on the eyes. Make your social media feed pop with your favorite colors. Cascadea lets you customize practically any website using custom CSS themes.
Welcome to Cascadea, the native custom style extension designed exclusively for macOS and Safari. Cascadea 2 is its biggest update yet, with a revamped UI for macOS Big Sur, a significantly improved extension, support for Apple M1, expanded UserCSS support, and more.
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